A trusted chemistry CRO to support drug discovery teams
Since 1999, our experienced scientists collaborate with global R&D teams from pharma and biotech companies on their next clinical candidate. Through all stages from Hit Identification to Lead Optimization and nomination of the candidate, our scalable FTE provide considerable added value by proactive consulting, execution and delivery of high quality chemistry. In a nutshell, we help our clients to reach their milestones faster and at lower costs!
Our drug discovery chemistry services include:
We routinely apply computer sciences in computational chemistry approaches and apply methods for structure-based drug design, in case structural data of the target…
High quality library design requires chemical creativity and profound synthesis knowledge to achieve the highest possible molecular diversity. Our efficient production…
Analytical chemistry and purification
Looking for integrated drug discovery services?
Committed to customers and success, we use all drug discovery approaches
We are exploring entry points into drug discovery and medicinal chemistry projects in an unbiased manner. High throughput screening (HTS) and focused screening yields typically good quality hits through additional counter screens to ensure hit validation. This approach allows for the highest level of serendipity. Our molecular design capabilities are following both structure- and ligand-based designs, as well as peptidomimetic techniques. Chemogenomics and fragment-based screening focuses on phylogenetic trees and good experience has been made across gene families when binding sites have been preserved. Selecting starting points from literature or IP knowledge yields traditionally high success rates with a shorter path to proof of concept (PoC) in animal models.