Integrated Drug Discovery

Holistic drug discovery to create new drug candidates

  • Medicinal chemistry from hit validation to candidate selection
  • Expertise on many biomolecular targets across all main therapeutic areas
  • Dedicated group for computational chemistry and molecular modeling
  • Partners for outsourcing disease biology, HTS, ADME, DMPK, X-ray crystallography
  • Strong track record in compound library design and production by parallel syntheses
  • Excellence in synthetic chemistry, process development as well as scale up to pilot plant

As Taros concentrates on drug discovery chemistry as core disciplines, discovery biology is typically outsourced to trusted and well-established partners as well as Drug Metabolism and Pharmacokinetics (DMPK), Absorption Distribution Metabolism Excretion (ADME), X-ray crystallography, and physico-chemical properties determinations. Taros’ Scientists worked on targets from all major gene families and across main therapeutic areas, such as oncology, neuroscience, cardiovascular and metabolic diseases, inflammation, autoimmune disorders as well as genetic and  rare diseases. On a routine basis, our team with a diverse educational and cultural background stays up to date with recent trends in academia and industry. As a guiding principle, in all of Taros’ partnerships and collaborations, our scientists are focusing on scientific excellence and quantity of output of work in a timely manner.

design and synthesis of peptide and peptidomimetics within medicinal chemistry research

Medicinal Chemistry

In Medicinal Chemistry research, we are working with a broadly experienced team on all biomolecular targets from any gene family in any therapeutic area. Our expertise…

Taros computational chemistry expertise encompasses the whole spectrum of computer-aided drug design, from virtual screening to adaptive SAR analysis as well as molecular modelling to statistical forecasting.

Computational Chemistry and Molecular Modeling

We routinely apply computer sciences in computational chemistry approaches and apply methods for structure-based drug design, in case structural data of the target…

Parallel chemistry and combinatorial chemistry for compound libraries and high throughput experimentation

Parallel Chemistry and Compound Libraries

High quality library design requires chemical creativity and profound synthesis knowledge to achieve the highest possible molecular diversity. Our efficient production…

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integrated drug discovery services?

Bioscience includes serveral approaches of assay development and in vivo pharmacology within the drug discovery process
Drug metabolism and pharmacokinetics and Absorption, Distribution, Metabolism, Excretion data are essential within the lead optimization phase to develop clinical candidates
Performing synthetic chemistry and medicinal chemistry to yield novel organic compounds with druglike physicochemical properties

Strong alliances and partnerships build up complementarity for your success

Together with our partners, we select the right set of drug discovery approaches and derive a coherent lead identification and optimization strategy based on available project and target information. Predefined criteria for meeting milestones and decision gates are typically agreed upon at the initiation of any project.

We are entertaining a strong network with academia, pharma partners and within the private-public partnership sector. Our alliances also encompass a broad range of chemical biology expertise, such as biocatalysis & metabolite identification, surface chemistry for mammalian cell handling, peptidomimetics, mimicking the hypervariable domain of antibodies (Abs) and fragments antigen binding (Fabs), therapeutic peptide approaches, design of ligands and precursors for positron emission tomography (PET) studies, as well as regenerative medicine approaches.

  • Veteran management team and highly qualified scientists with relevant industry experience and a drug-hunting mentality
  • We are agnostic to the type of drug discovery approach, we focus on the success
  • Well-established network of partners for outsourcing disease biology, ADME, DMPK, etc. 
  • Strong academic and industrial Alliances encompassing a broad range of structural and chemical biology expertise, such as metabolite identification, therapeutic peptide approaches, etc.
  • Experienced in the management of great research consortia like the European Lead Factory (ELF) consisting of 30 Partners
  • 20 years of excellence in custom synthesis and organic chemistry research ensure molecules with optimised properties and patentability
  • Own multi-purpose pilot plant facility in Asia for large-scale syntheses and with access to a broad supplier network for building blocks, etc.
synthetic organic chemistry

Custom Synthesis

As a leading Contract Research Organization in Europe, Taros provides valuable contract discovery for synthetic organic chemistry, chemical process development, and pilot plant manufacturing services to meet our clients’ needs at…

therapeutic areas

Indications and Gene Families

We provide expertise on G-protein coupled receptors, nuclear (hormone) receptors, enzymes and transporters, ion channels, as well as protein-protein interactions and targeting RNA as a drug target. Our team explores…

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As a leading CRO in Europe, Taros provides comprehensive drug discovery chemistry services for large Pharma and Biotech corporations as well as for Research Institutes and Academia

Our experienced chemists practice a pragmatic culture and customer-centric approach in order to exceed project expectations, despite challenges, bridging very narrow timelines. They are trained to consider economic, safety and ecological boundaries and conditions laid out for all stages of the project, starting from the development of synthetic routes to…