Tissue engineering is one of the most promising therapeutic approaches in modern medicine in the future and offers the chance of giving new healings to millions of people. Previously established carrier polymers have a high rigidity and do not adapt to the requirements of the cells cultivated on them…
Regenerative medicine: Taros and Uni Koeln want to improve tissue culture Read More »
Anna Karawajczyk, Fabrizio Giordanetto, Jorg Benningshof, Daniel Hamza, Tuomo Kalliokoski, Kees Pouwer, Remy Morgentin, Adam Nelson, Gerhard Müller, Alexander Piechot, Dimitrios Tzalis
Drug Discovery Today (2015)
Just a few months after its inclusion for drug target screening, one of the first compounds synthesised within the European Lead Factory was identified as a ‘drug-like’ hit. The compounds were synthesised by the Public Chemistry Consortium, based on library…
Chemical & Engineering News
ISSN 0009-2347: Copyright © 2015 American Chemical Society
Europe’s Contract Research Firms Look Downstream Read More »
Hugh Laverty, Kristina Maria Orrling, Fabrizio Giordanetto, Magali Poinot, Eckhard Ottow, Ton Wilhelmus Rijnders, Dimitrios Tzalis and Stefan Jaroch
Journal of Medicines Development Sciences (2015)–Volume 1, Issue 1
The European lead factory – an experiment in collaborative drug discovery Read More »
Sankar MG, Mantilli L, Bull J, Giordanetto F, Kumar K, Waldmann H
Bioorg Med Chem Lett 2014
Ortega R, Sanchez-Quesada J, Lorenz C, Dolega G, Karawajczyk A, Sanz M, Showell G, Giordanetto F
Bioorg Med Chem Lett 2015, doi:10.1016/j.bmc.2015.01.046
Design and Synthesis of 1,1-disubstituted-1-Silacycloalkane-based Compound Libraries Read More »
Murali A, Medda F, Winkler W, Giordanetto F, Kumar K
Bioorg Med Chem Lett 2014
Branching cascades provide access to two aminooxazoline compound libraries Read More »
INS, ISAS, MPI-Do, WTZ, LDC
Taros Chemicals
Drug Discovery Engine DDE based on natural products Read More »
It’s early 2015 and the latest European Lead Factory Newsletter is now out. Take a look and discover interesting news and results of this unique European Drug Discovery initiative…
European Lead Factory Newsletter January 2015 Read More »