Analytical Chemistry and Purification
Compound purification and quality control
- (u)HPLC, LC/MS
- NMR spectroscopy
- Reaction calorimetry
- Viscosimetry/rheology
- Polarimeter
- GC-MS
- FT-IR and IR spectroscopy
- Differential scanning calorimetry (DSC)
- Dynamic light scattering (DLS)
- Melting point determination
- Preparative HPLC
- UV/VIS spectroscopy
- Thermal gravimetric analysis (TGA)
- Gel permeation chromatography (GPC)
- Karl Fischer Titrator
Chemical composition analyses utilize a combination of techniques that can cover a wide range of applications and determine chemical quality, identity, composition and impurities, with molecular structure elucidation and chemical structure confirmation provided by our analytical expertise. Within analytical chemistry, Taros scientists use mass spectrometry techniques to determine molecular weight and various approaches to provide valuable data in the identification of an unknown molecule. During the process, they apply techniques such as 1H and 13C nuclear magnetic resonance (NMR) to explore and confirm the connectivity of the atoms in the molecule. They also apply a range of techniques including chromatography approaches to study and confirm optical isomers of chiral molecules.
Looking for analysis and purification of your intermediates and products?
Medicinal Chemistry
Custom Synthesis
Looks interesting?
As a leading CRO in Europe, Taros provides comprehensive drug discovery chemistry services for large Pharma and Biotech corporations as well as for Research Institutes and Academia
Frequently Asked Questions
Taros provides analytical support for starting materials, intermediates, final compounds and process-development projects. Available techniques include NMR, LC-MS, GC-MS, FT-IR, UV/VIS, DSC, DLS, GPC and chiral analysis, together with chromatographic purification methods selected according to the compound, required purity and project scale.
Yes. Taros combines chromatographic and spectroscopic methods to detect, isolate and characterise impurities or unknown components. Depending on the project, the work can include purity assessment, molecular-mass confirmation, structural analysis, impurity isolation, comparison with synthesised reference compounds and preparation of analytical documentation.
Taros supports analytical chemistry and purification requirements from milligram-scale research samples to larger gram and kilogram-scale chemistry projects. The analytical and purification strategy is selected according to the sample quantity, compound properties, required purity, intended application and the amount of material that must be recovered.